What is the induced fit model of enzyme action?

• A. The enzyme active site is rigid and does not change shape upon binding.
• B. The enzyme's active site undergoes conformational changes upon substrate binding to better fit the substrate and stabilize the transition state.
• C. Substrates are completely pre-shaped to fit the active site without any change.
• D. Enzymes change their primary sequence to accommodate substrates.

Answer: (B)